The following lifestyle changes can help trigger your cellular detox system, i.e., autophagy:
Fasting
Intermittent fasting can help induce autophagy. A hunger break of 14-18 hours automatically shifts your body to a survival mode that helps:
- Activate autophagy
- Enhance AMPK activation
- Shuts down mTOR
The following are the benefits of intermittent fasting:
- Improved metabolism
- Brain clarity
- Reduced inflammation
- Anti-aging
Exercise
Both cardio exercise and strength training help activate autophagy. Autophagy also helps:
- Maintain mitochondrial efficiency
- Eliminate oxidative stress
- Promote longevity
Caloric Restriction
Calorie restriction helps:
- Improve autophagy
- Extend lifespan
- Lower insulin levels
- Maintain glucose levels
- Promotes fasting-like state
Low-Carb or Ketogenic Diets
A low-carb or ketogenic diet can help naturally:
- Maintain insulin levels
- Activate AMPK
- Inhibit mTOR
These are the ideal conditions for fasting and autophagy activation.
Heat and Cold Exposure
Heat and cold exposures are popular. These are called hormetic stressors. These can help encourage cellular resilience and kickstart autophagy-related pathways.